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Importantly, L2-Cmu treatment in females did not adversely affect cardiac function, but instead restored diastolic function to more youthful levels (Fig
10 Existen mltiples mecanismos moleculares que pueden producir resistencia a la accin fisiolgica de la insulina: Como los defectos prerreceptor (alteracin en la molcula de insulina) y la existencia de receptores anmalos para la insulina (por mutaciones genticas)
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