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For Indian skin (Fitzpatrick IVVI) Tranexamic acid has been shown to be particularly relevant for Fitzpatrick skin types III-VI, as research indicates these populations experience higher incidence and severity of post-inflammatory hyperpigmentation and melasma with increased tendency toward relapse

Maintenance programs following an initial course are available and are individualized based on clinical response and long-term goals

The affected genes included critical "node molecules" (YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2) involved in regulating multiple biochemical pathways

and the failure of the immune system combined with the loss of GSHs protective effect as an antioxidant may explain the progression of the disease into acute respiratory distress syndrome/acute lung injury