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Tasoulis, M
Statistical analysis All results were expressed as mean s.e.m
The extrinsic pathway is driven by extracellular or membrane-associated events, including increased iron uptake via transferrin receptor 1 (TFR1) or inhibition of the xc-cystine/glutamate antiporter system, leading to cysteine depletion and impaired glutathione synthesis
Both combinations leverage cagrilintide's amylin pathway activation, but they differ significantly in their complementary mechanisms
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