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nonsmoker Clinical impression: Class II obesity PCOS by Rotterdam criteria (ovulatory dysfunction + clinical hyperandrogenism), excluding secondary causes Insulin resistance with hyperinsulinemia and prediabetes Dyslipidemia , possible MASLD Binge eating disorder with restriction-anxiety-binge cycles Anovulatory infertility risk Goals: Reduce cardiometabolic risk and normalize ovulation/fertility potential Stabilize insulin and lipids
That discovery launched over four decades of continuous scientific investigation, and what researchers have found since then paints a compelling picture
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