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Cell (2017) This landmark Cell publication from Erasmus University Medical Center introduced FOXO4-DRI as a senolytic peptide that selectively eliminates senescent cells by disrupting the FOXO4-p53 interaction
GLP-1s work on incretin pathways to slow digestion and increase fullness
The exact cause is not fully understood, but it may relate to the bodys response to the drug or dehydration
NNMT is overexpressed in obese adipose tissue and is theorized to deplete SAM and NAD+ pools in adipocytes, contributing to metabolic dysfunction
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