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Vitamin B12 acts as a cofactor for the enzyme methionine synthase, which is crucial for DNA synthesis
According to current statistics, cases of unwanted side effects are very rare
After this period, peptide degradation may reduce bioactivity
To provide different perspectives on the estimated treatment effect in weight management RCTs, we recommend that future publications investigating new or already-approved weight-loss medications report the treatment policy estimand and the trial product estimand
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