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Recently, researchers developed a translational pharmacokinetic and pharmacodynamic model by integrating in vitro and in vivo data in a mechanistic and quantitative manner, which revealed a dose-dependent reduction in the cardiac amyloid burdenoccurring within 4 months at 60 mg/kg and within 10 months at 10 mg/kg
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For this particular population of boys, could a viable preventative strategy be simply to ensure carnitine is provided in the diet as an infant goes from carnitine-rich milk as their primary food, to juices, fruits, and other foods containing reduced amounts of carnitine
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