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Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction
95% CI, 0.79-0.99) and mostly in a primary prevention population, while SURPASS-CVOT is entirely secondary prevention with wider use of modern therapies like SGLT2 inhibitors
J.JagannathS.RajeN
The most frequent side effects include nausea, vomiting, constipation, and diarrhea, particularly during dose escalation
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