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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis
Topical application delivers GHK-CU directly to skin tissue
an unusual or allergic reaction to cyanocobalamin, cobalt, other medicines, foods, dyes, or preservatives
A patch test on the inner forearm for several days before facial application is a simple, evidence-aligned precaution that can reveal an allergic tendency before it affects a more visible or sensitive area
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