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A 2026 UK review of the Molecular Psychiatry meta-analysis of 31 trials, the 2:1 caffeine + L-theanine stack, the alpha-wave and GABA mechanism, the sleep and stress data, the honest EFSA caveat and its excellent safety versus Dihexas unproven HGF/c-Met synaptogenesis and the c-Met concern
There are no known interactions between the two, and they are commonly included together as part of a daily wellness routine
Mild to moderate nausea following an accidental overdose, while unpleasant, is usually self-limiting
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(June 2002)
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