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The same reaction can occur on protein cysteine, and the formed GSNO group functions as important intermediate in NO metabolism, a critical player in fulfilling the biolgogical function of NO in signal transduction ( S -glutathionylation (Zeng et al., 2001) or thanks to catalytic activity of GGT generate S-nitrosocysteinylglycine that in turn can be cleaved by a membrane dipeptidase thus forming S -nitrosocysteine (S-NO)

Bariatric surgery offers a more permanent solution by addressing the root causes of obesity, unlike GLP-1 receptor agonists, which often require long-term use and come with potential side effects such as gastrointestinal symptoms, thyroid tumors, and kidney injury

Starting weight, lifestyle habits, medical conditions, treatment adherence, and provider recommendations all influence outcomes

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