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Journal of Endocrinological Investigation, 47 (6), 13951403
The half-life of oral semaglutide was also ~ 1 week in both groups, which was comparable with subcutaneous semaglutide and illustrates that the half-life is not determined by the mode of administration [65]
It adds that a provider must assess contraindications, baseline kidney function, and medication interactions before recommending anything, and it states flatly that cost should never override clinical safety when weighing the more affordable choices
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