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In a study by Kim et al., a tissue adhesive and anti-inflammatory hydrogel was developed by forming high-affinity enzymatic cross-linking of polyphenolic Epigallocatechin gallates (EGCGs) (Fig
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In addition, lysine demethylase 4C (KDM4C) can also increase the expression of SSP genes by directly demethylating the promoter of SSP genes or ATF4, a transcriptional substrate of NRF2 (Denicola et al., 2015
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