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Description

GLP-1 drugs, such as Ozempic and the combination drug tirzepatide also included in the study, mimic a natural hormone known as glucagon-like peptide-1 to help regulate blood sugar and insulin levels

10.1177/20503121241308997 SAGE Open Med

Our study describes a novel action of GLP-1 signalling in -cells, which stimulates metabolic/bioenergetic reprograming resulting in a high glycolytic/high ATP generating phenotype, as detailed in (Fig

But the glucagon receptor activation, which drives fat oxidation and improves lipid profiles, takes 12 to 24 weeks to fully show up in blood work and body composition