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Vomiting was reported by 24% of the patients, diarrhea by 30%, constipation 24%, abdominal pain 20%, headache 14%, fatigue (tiredness) 11%, indigestion 9%, dizziness 8%, abdominal bloating 7%, flatulence 6%, loud burping 7%, low blood sugar (hypoglycemia) 6% and other side effects

Retatrutide has the potential to enhance weight reduction outcomes and manage obesity-related comorbidities like diabetes and hypertension (high blood pressure) when paired with a healthy diet, consistent exercise, and lifestyle adjustments

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The FDA similarly removed it from its shortage list on February 21, 2025, but this time, it designated off-ramps for production of compounded types right off the bat: Technically, 503A pharmacies have until April 22 to quit making semaglutide drugs, while 503B facilities have until May 22