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Importantly, as shown in the first row, LASSS supplementation effectively prevented an increase in the nitration level of ECM-HGF, whereas GSSSG did not demonstrate efficacy, inconsistent with its potent potential shown in in vitro experiments described earlier (see Figure 1b)

The extensive hydrogen bonds formed between CME_d and the pocket residues lead to greater stability in the surrounding residues compared to CME_c (Fig

Abstract Heart Failure with Preserved Ejection Fraction (HFpEF) represents a significant challenge in modern cardiovascular medicine, characterized by diastolic dysfunction and a chronic pro-inflammatory milieu

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