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Clinical Features The lesions present as blue-black plaques or nodules averaging 1 cm in diameter, but with some lesions measuring several centimeters, without a predilection for site or sex
While several E3 ligases were found in complex with NHR-49::GFP in vivo under fasted conditions 42 , we chose the top two interactors to screen: the WW domain-containing E3 ligase, WWP-1, and HECT domain E3 ligase, HECD-1
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