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This is the case for both Aetna and Blue Cross Blue Shield , for instance
For the functional items in the EQ-5D, these were dichotomised as 1 (no problems) vs 23 (any problems)
However, a recurrent pattern observed across numerous studies is that this association is more consistent for physical aspects of HRQoL than mental aspects [38,39,40]
It remains unclear whether these reactions result from direct drug effects or immune-mediated responses
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