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Studies using fetal lung fibroblasts found GHK induces dose-response gene expression changes in 329 genes associated with extracellular matrix composition
Therefore, the product expires, even before its shelf-life
This influences how long visible improvement continues
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
