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Note areas of thinning, recession, or concern

Healthcare providers may recommend checking blood glucose levels during the night or using continuous glucose monitoring to identify nocturnal hypoglycemia

But now this is increasingly being noted in people and prompted The Atlantics Sarah Zhang to publish a piece entitled "Did Scientists Accidentally Invent an Anti-addiction Drug? The studies in people are limited, such as cases series for cocaine addiction and a small randomized trial for alcohol use disorder, which included fMRI

Key Points The discovery of androgen dependence in prostate cancer in 1941 by Huggins and colleagues still remains the backbone for the treatment of advance-staged prostate cancer Over the past decade, the better understanding of the mechanisms driving resistance to castration has led to development of abiraterone acetate and enzalutamide, two next-generation androgen receptor (AR) targeting agents Several challenges remain including resistance to continued blocking of the AR axis, cross-resistance between agents, ideal sequence of administration, combination strategies, and coordination with other treatments Molecular characterization of patients, through next-generation sequencing or transcriptome analysis, will help to dissect mechanisms of resistance and to identify biomarkers allowing the selection of patients for specific treatment The improved understanding of intra-patient molecular heterogeneity and of the multiple, redundant and compensatory signalling networks in cancers supports a role for rational combinatorial, targeted therapeutic approaches Abstract The discovery of androgen dependence in prostate cancer in 1941 by Huggins and colleagues has remained the backbone for the treatment of this disease