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Thus, bariatric surgery still occupies a critical role in advanced obesity management
This strategy has been exploited in the long-acting GLP-1RA semaglutide (Novo Nordisk), for instance, which was approved for treatment of T2DM in 2017, and for treatment of obesity in 2021, and has since then become the most prescribed GLP-1RA 92
For laboratory handling it is typically reconstituted in bacteriostatic water
N Engl J Med 385:22522263 Giugliano D, Esposito K, De Nicola L (2024) Diabetic kidney disease: the fourth pharmacological pillar may be semaglutide
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