doi: 10.1038/s41574-019-0176-8 9 MaCAvenellABollandMHudsonJStewartFRobertsonCet al
123,132 In melanoma, BRAFi/MEKi-induced reactivation of MAPK signaling in tumor cells promotes the secretion of CXCL1, HGF, and TGF-, thereby recruiting cancer-associated fibroblasts and immunosuppressive myeloid cells and remodeling the extracellular matrix to generate a drug-resistant microenvironment
You are pharmacologically stimulating melanocytes, or the pigment producing cells in the skin, which raises safety questions, she says
In addition to broccoli, watercress, and mustard greens, consider including: Allium vegetables Garlic, leeks, onions, scallions, and shallots Cruciferous vegetables Arugula, broccoli, cabbage, cauliflower, kale, and radishes Legumes Chickpeas, faba beans, kidney beans, lentils, and peas Nuts and seeds almonds, brazil nuts, walnuts, sesame seeds, and sunflower seeds #2 Foods Rich in Vitamin C Combining glutathione with vitamin C may help boost glutathione levels