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The dedicated cardiovascular outcomes trial TRIUMPH-Outcomes, enrolling ~10,000 participants over roughly 5 years is the study designed and powered to answer the cardiovascular benefit question definitively
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Randomized controlled clinical trials investigating the use of semaglutide in patients with alcohol use disorders (AUD) and comorbid obesity are currently underway, based on the potential of GLP-1R agonists for AUD treatment [113]
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