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However, the SUSTAIN six trial evaluated semaglutide, a GLP-1 analog, in patients with type 2 diabetes and high cardiovascular risk and discovered that semaglutide was associated with a higher incidence of diabetic retinopathy complications compared to placebo, with a hazard ratio (HR) of 1.76, particularly in patients with pre-existing DR (Vilsbll et al., 2018)
Most common side effects resolve within weeks, but understanding the exact timeline helps set realistic expectations during the transition period
Most people find that the semaglutide appetite suppression kicks in before they finish the half portion
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