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Excess iron ions are either stored in ferritin heteropolymers in the form of Fe 3+ or are released extracellularly via the membrane protein ferroportin
Serious side effects are uncommon when therapy is properly dosed and medically supervised
Cautions for the wider drug class Class-level Approved GLP-1 medicines carry label warnings about pancreas inflammation, gallbladder problems, thyroid tumours seen in rodent studies, and low blood sugar when combined with insulin or sulfonylureas (a diabetes drug group)
Notably, total IGF-I and IGFBPs were unchanged over this short-duration window, dissociating the observed bone-growth effect from sustained IGF-1 axis activation in this model
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