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This has been demonstrated in multiple studies with rats and swine, where growth hormone levels significantly increased after injections without impacting ACTH and cortisol plasma levels: In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml)

Anti-asthma simplified herbal medicine intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-, but not transforming growth factor- dependent

H2S = hydrogen sulfide)

Low-dose glutathione administration in the prevention of cisplatin-induced peripheral neuropathy in rats