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They have realistic expectations about the side effect profile and are willing to tolerate gastrointestinal discomfort in the early weeks

Laser and Energy-Based Treatments For specific, localised pigmentation concerns such as solar lentigines, freckles, and discrete hyperpigmented lesions laser treatments offer targeted, evidence-supported options: Q-switched Nd:YAG laser : Delivers short, high-energy pulses that fragment melanin deposits

This treatment is especially popular among busy professionals, athletes, and anyone with a demanding lifestyle

This accumulation leads to disulfide stress, ultimately resulting in cell death through a novel form of programmed cell death known as disulfidptosis (64)