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Indeed, phase 3 clinical trials of retatrutide for type 2 diabetes, non-alcoholic fatty liver disease, and obesity are presently underway (Supplementary Table S2) 10

Future investigations employing sequential single-cell transcriptomics, specific inducible gene knockouts, and clinical cohort stratification are urgently needed to elucidate these temporal dependencies, which will pave the way for precise, stage-targeted RCD-modulating therapies in DKD

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Start With Retatrutide Alone as the Evidence Baseline Retatrutide is one molecule that activates GLP-1, GIP, and glucagon receptors