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Overall, interventions with various polyphenolsincluding sesamol, quercetin, Q3G, Triphala, ginger, pterostilbene, curcumin, polymannuronic acid, and CAconsistently elevated key metabolites such as SCFAs, which were associated with improved cognitive function, reduced neuroinflammation, and enhanced gut-brain axis activity in both AD and PD models [32, 33, 36,37,38, 41, 42, 44, 45]

Introduction Cysteine, a sulfhydryl-containing proteinogenic amino acid essential for the human body, is employed in a variety of metabolic pathways, such as the regulation of reduced glutathione (GSH), a major endogenous antioxidant molecule and the generation of sulfur-containing biomolecules such as hydrogen sulfide (H 2 S), taurine, coenzyme A and biotin ( Figure 1 ) ( Figure 1 Cysteine metabolism in cancer and tumor microenvironment It is increasingly noted that altered levels of amino acids including cysteine in the tumor microenvironment, by uptake or processing of both intracellular and extracellular regions, have emerged as potential markers of tumor progression

Best Forms and Dosages Glutathione Options Reduced Glutathione: The most common form, but absorption can be limited

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