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confirmed that TFAP2C regulated GPx1 expression by directly binding to the GPx1 promoter, which contains an AP-2 regulatory region, and the methylation of the CpG island in the GPx1 promoter region prevented the binding of TFAP2C by encompassing the AP-2 regulatory region [81]
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Analysis of tooth plaque from Neanderthals in Europe suggests that they ate a wide variety of plant foods including cooked grains and legumes, although teeth from some sites suggest a mostly animal-based diet while others suggest a mostly plant-based diet
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