Uptake is being accelerated by increased patient compliance and a preference for non-invasive treatments
Glasner discusses who might benefit from these medications, important limitations of the current research, and why GLP-1s should be viewed as a potential toolnot a curewithin a broader, evidence-based approach to addiction care
J Gen Physiol 129:233244 Yang Y, Shu X, Liu D, Shang Y, Wu Y, Pei L, Xu X, Tian Q, Zhang J, Qian K, Wang YX, Petralia RS, Tu W, Zhu LQ, Wang JZ, Lu Y (2012) EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation
They also activate pathways such as Keap1/Nrf2/ARE, reinforcing cellular antioxidant defenses without direct ROS neutralization 149