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The guidelines warn, however, that GLP-1 receptor agonist therapy is not indicated for all patients and should be used with caution in patients with a history of significant gastrointestinal disease, such as a diagnosis of gastroparesis, due to a possible exacerbation of the condition with incretin mimetic therapy
The present recommendations of the American and European Diabetes Associations are currently updating their actual recommendation for the treatment algorithm for T2D ( Tirzepatide may also become an important pharmacological tool for the treatment of obesity if data from the SURMOUNT-1 trial are confirmed in other clinical studies (82)
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