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The coating-protected method of Smartamine is based on the pH differences between the rumen and abomasum, and the release of the AA will depend on the environmental pH

Induction of in vitro chemotherapeutic drug resistance by activation of Raf/MEK/ERK or PI3K/PDK/AKT signal transduction pathways in MCF-7 breast cancer cells

Cross-disease comparisons suggest that these modules recur across different organ niches, but their net effects are markedly context-dependent and are jointly regulated by disease stage (acute inflammation versus chronic tissue remodeling), tissue compartment (peripheral blood versus lesional tissue), as well as the spectrum of stimuli and therapeutic exposure, thereby leading to inconsistent directional outcomes of the same pathway across different models and time windows

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