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This review presents a concise history of the discoveries of GIP and GLP-1, explores the physiology and pharmacology of incretins and their synthetic mimetics, and discusses the therapeutic applications of the USA FDA-approved GLP-1 and dual GIP/GLP-1 receptor agonists

doi: 10.1139/H07-174, 8

For instance, the administration of glucagon receptor antagonists increased hepatic fat content and plasma concentrations of LDL-cholesterol in people with type 2 diabetes [51]

Subsequently, the samples were dehydrated using a graded ethanol series, embedded in paraffin, and sectioned to a thickness of 7 m using a microtome