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Based on Phase 2 trial data (Jastreboff et al., NEJM 2023), injection site reactions with retatrutide were among the more commonly reported adverse events, occurring across multiple dose groups

However, because of high levels of endogenous C

Now, leading medical organizations like the World Health Organization recognize obesity as a chronic medical condition that can drive numerous other health ailments such as diabetes, heart disease, kidney disease and potentially even cancer

Both transporters have been shown to efflux folates from intestinal enterocytes and, as such, can compete with the activity of PCFT in folate uptake