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Improves skin hydration, texture, and elasticity alongside whitening
arXiv Systematic Reviews / Meta-analyses A recent systematic review on type 3 diabetes draws together evidence of overlapping mechanistic pathways, supporting the idea that agents targeting insulin resistance (including GLP-1 RAs) might have benefit
In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)
and the Giorgio Foundation
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