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Characterized by insulin resistance, gradual progressive loss of insulin secretion by -cells, and being heavily driven by being overweight or obese [98], T2DM leads to hyperglycemia, excessive urine production, increased risk of cardiovascular disease, and changes in energy metabolism [106]
Animal studies show GLP-1 receptor agonists cause fetal harm, including reduced fetal weight and skeletal abnormalities
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While not a primary application, peptides such as GHK-Cu may be used off-label to improve lip firmness and reduce fine perioral lines
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