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These observations suggest that during pharmacological GLP-1R agonism, the net effect of -arrestin recruitment is to reduce prolonged insulin release

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Semaglutide is a synthetically manufactured hormone resembling 95% of the naturally occurring GLP-1

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doi: 10.1016/S0090-4295(96)00313-5 60 SalehRAAgarwalASharmaRKNelsonDRThomasAJJr

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