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This is a common question, and the frustration of patients due to high costs is understandable

High cost and insurance restrictions are common, with many plans requiring step therapy, higher BMI, or documented inability to lose weight by other methods before approval. Do GLP-1 drugs replace the need for arthritis or autoimmune medications

Whether or not people can successfully de-escalate could be related in part to how they metabolize the drug and the length of that steady state, Pinto says

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