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These findings showed a decrease in the production and secretion of IFN- by IELs in the gut following the administration of the GLP-1RAs semaglutide and exendin-4 [165]

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Baseline and ongoing monitoring: Before initiating GLP-1/GIP therapy, consider measuring baseline B12 levels, particularly in patients concurrently taking metformin, those with previous bariatric surgery, individuals following plant-based diets, or those with malabsorption conditions

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Darios F, Muriel MP, Khondiker ME, Brice A, Ruberg M

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