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TNF- is found at high levels in the synovium of patients with RA [234], while IL-1 is recognized as a major contributor to inflammation in the disease [235]
508 Patients with severely active UC received intravenous infliximab (5 or 10 mg/kg) at weeks 0, 2, and 6, and more than 60% of patients experienced a significant response at week 8
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Were still learning, Salkin said
