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Molecular docking has shown that icariin can bind c-Jun through hydrogen bonds, with a binding affinity of 11 kcal mol 1 (Gao et al., 2023)

Kleuss C, Krause E

The theory is that boosting HGH levels could help counter some of the changes that often accompany midlife, from increasing belly fat (hello, meno belly) to declining muscle mass and lower energy levels (hello, 3am club)