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Particularly in oncology patients who exhibit insensitivity to initial therapeutic agents and demonstrate resistance to radiotherapy and chemotherapy interventions (31)
But calling it nature's Ozempic is marketing fiction
Additionally, combination therapy is becoming more common
Treatment with rapamycin, a known inducer of autophagy, led to an increase in LC3B puncta and a decrease in P62, whereas treatment with wortmannin, an inhibitor of early-stage autophagy, shows the inverse pattern (Figure 1)
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