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Long-Term: Continuous use is associated with a prolonged lifespan, enhanced cardiovascular health, and sustained improvements in physical and cognitive performance
This is reasonable for pharmaceutical-grade product
CSF and blood neurofilament levels in athletes participating in physical contact sports: a systematic review
Unlike peptides that require brain penetration, klotho enhances cognition when administered peripherallydespite not crossing the blood-brain barriersuggesting it acts through systemic signaling mechanisms that remain incompletely understood
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