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In the large SELECT clinical trial, semaglutide 2.4mg (the active ingredient in Wegovy) was shown to reduce the risk of major cardiovascular events by 20% compared with placebo

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Not dramatically, not all at once, but slowly

Therefore, nutraceutical skin applications using collagen and antioxidants such as curcumin and glutathione demonstrate hopeful results for dermal antiaging effects, especially in estrogen-deficient skin