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It was more effectively activated by elevated levels of GSH in H1299 lung cancer cells than that in normal lung fibroblasts WI38 cells, releasing reactive alkoxyamines to capture AP sites, blocking APE1 repair, and leading to lung cancer cell death in vitro
The TB-500 component thymosin -4 is prohibited at all times under section S2 of the WADA Prohibited List (peptide hormones, growth factors, related substances and mimetics), which expressly names thymosin--4 and its derivatives
Hara, M., Harazaki, A
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