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Copper peptides are generally safe for most people when used topically, as they don't enter the body to produce systemic effects, but copper peptides might not be appropriate for people with a known allergy or sensitivity to copper
Free radicals can cause cell damage
Look for non-comedogenic options that won't clog pores whilst providing gentle brightening effects
FOXO4-DRI is a large peptide (~5382 Da, 48 amino acids) with a critical structural modification: the D-Retro-Inverso (DRI) design uses D-amino acids in reversed sequence to confer protease resistance while maintaining the 3D spatial arrangement needed for target binding
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