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AstraZeneca said the antibody-drug conjugate, acquired through its 2023 licensing deal with KYM Biosciences, has blockbuster potential with projected peak sales of $3 billion to $5 billion
film thickness 1.0 m) (GL Sciences, Tokyo)
Its main role is to protect cells from oxidative stress and support many metabolic processes, especially in the liver
Furthermore, bile acid dysregulation, characterized by low conjugated primary bile acids and high hydrophobic secondary bile acids, stimulates FXR and TGR5 signaling pathways, exacerbating intestinal inflammation and modulating lipid metabolism [49]
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