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The fat-to-lean mass ratio improved from 0.93 at baseline to 0.70 at week 72 in the tirzepatide group, compared to 0.95 to 0.88 in the placebo group
But between 2022 and this year, compounded versions of these medications had sometimes become a more accessible and affordable option for patients
Costs depend on diagnostics, type of treatment, duration, follow-ups, etc
There is also the burden of an injectable treatment and its high cost: Ozempic and Wegovy are expensive (often around $900$1,300 per month without insurance), and insurance coverage for weight-loss use is inconsistent
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