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They also help manage metabolic-associated steatotic liver disease
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0.2 years in diabetic patients with cardiovascular risk factors only, suggesting an additional benefit of semaglutide in this population with high cardiovascular risk.88 The mechanisms involved in the cardiovascular benefits of this family are various
In people with obesity, 36 weeks of orforglipron (doses ranging from 12 to 45 mg in a phase 2 trial) resulted in a dose-dependent WL up to 14.7% compared to 2.3% with placebo, with concomitant improvement in cardiometabolic risk factors (Table 2) [25]
